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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPA
All Species:
3.33
Human Site:
T23
Identified Species:
5.24
UniProt:
P49450
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49450
NP_001035891.1
140
15991
T23
R
S
P
S
P
T
P
T
P
G
P
S
R
R
G
Chimpanzee
Pan troglodytes
XP_515346
138
15774
G23
R
S
P
S
P
T
P
G
P
S
R
R
G
P
S
Rhesus Macaque
Macaca mulatta
XP_001087306
138
15765
G23
R
S
P
S
P
T
P
G
P
S
R
R
G
P
S
Dog
Lupus familis
XP_532899
135
15196
R23
S
P
A
P
S
A
P
R
R
G
P
S
L
G
T
Cat
Felis silvestris
Mouse
Mus musculus
O35216
134
15491
R23
S
P
A
P
G
P
S
R
Q
S
S
S
V
G
S
Rat
Rattus norvegicus
P84245
136
15309
T23
A
P
R
K
Q
L
A
T
K
A
A
R
K
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509693
121
13998
Q27
R
R
Y
R
P
G
K
Q
V
L
K
E
I
R
R
Chicken
Gallus gallus
Q6XXM1
131
15224
P24
P
A
A
P
P
P
P
P
A
R
P
R
A
R
R
Frog
Xenopus laevis
Q569M3
150
17325
R32
T
T
S
R
T
S
P
R
R
P
H
A
Q
Q
Q
Zebra Danio
Brachydanio rerio
Q803H4
145
16662
P25
R
S
P
P
A
S
L
P
P
P
A
G
S
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02299
136
15370
T23
A
P
R
K
Q
L
A
T
K
A
A
R
K
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10453
136
15323
T23
A
P
R
K
Q
L
A
T
K
A
A
R
K
S
A
Sea Urchin
Strong. purpuratus
P06352
136
15483
T23
A
P
R
K
Q
L
A
T
K
A
A
R
K
S
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LR02
136
15384
T23
A
P
R
T
L
L
A
T
K
A
A
R
K
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RXR3
155
17319
P29
P
T
P
K
A
T
P
P
G
R
R
K
S
R
A
Conservation
Percent
Protein Identity:
100
98.5
92.8
77.1
N.A.
70
45
N.A.
60
58.5
54.6
55.1
N.A.
44.2
N.A.
44.2
44.2
Protein Similarity:
100
98.5
93.5
83.5
N.A.
80.7
56.4
N.A.
72.8
71.4
67.3
64.8
N.A.
57.1
N.A.
56.4
57.1
P-Site Identity:
100
53.3
53.3
26.6
N.A.
6.6
6.6
N.A.
20
26.6
6.6
33.3
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
53.3
53.3
26.6
N.A.
6.6
13.3
N.A.
20
33.3
40
40
N.A.
13.3
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
N.A.
47.7
Protein Similarity:
N.A.
N.A.
N.A.
58.5
N.A.
61.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
7
20
0
14
7
34
0
7
34
40
7
7
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
7
0
14
7
14
0
7
14
14
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% I
% Lys:
0
0
0
34
0
0
7
0
34
0
7
7
34
0
0
% K
% Leu:
0
0
0
0
7
34
7
0
0
7
0
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
14
47
34
27
34
14
47
20
27
14
20
0
0
14
0
% P
% Gln:
0
0
0
0
27
0
0
7
7
0
0
0
7
7
7
% Q
% Arg:
34
7
34
14
0
0
0
20
14
14
20
54
7
34
14
% R
% Ser:
14
27
7
20
7
14
7
0
0
20
7
20
14
34
20
% S
% Thr:
7
14
0
7
7
27
0
40
0
0
0
0
0
0
14
% T
% Val:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _